Bioprinting is a process where biomaterials such as hydrogels are combined with cells and/or signaling molecules and are printed to create tissue-like structures. These structures can be used for drug screening, disease modeling, and tissue regeneration. In our lab, we derive bio-inks from natural and synthetic hydrogels, decellularized tissues, and minimally modified human tissue, such as peripheral blood. The developed bio-inks are tested for printability, post-printing cross-linking, and cell compatibility. TEST Lab has a state-of-the-art CELLINK bioprinter,which supports thermoplastic polymer printing, hydrogel printing, and their combination, to generate tissue-like structures with mechanical compatibility. Current projects in this area include the development of decellularized cartilage bio-inks and bioprinting to generate live cartilage and osteochondral tissue structures. Our goal is to extend this method to other musculoskeletal tissues and interfaces.